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Proteomics search & quantification so fast that it feels easy

AGPL-3.0bioengineering/proteomics
★ 500
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A high-performance proteomics search and quantification engine for peptide identification from tandem mass spectra.

About the Project

Why use this?

Sage is a fast proteomics database-search and quantification tool for identifying peptides from tandem mass spectra. It is designed to deliver high-performance search and quantification while remaining straightforward to operate in modern proteomics workflows.

Proteomics engineers choose Sage when they need rapid peptide-spectrum matching and quantitative analysis without the operational overhead of older search pipelines. Its interoperability with OpenMS, where Sage is available as a TOPP tool, makes it practical to embed in broader LC-MS/MS analysis workflows. [299]

Key Features

  • High-performance proteomics search and quantification
  • Peptide identification from tandem mass spectra
  • Fast, modern search-engine architecture
  • OpenMS interoperability through a TOPP tool integration
  • Suitable for large-scale LC-MS/MS proteomics workflows
Replaces / Alternative to
Mascot, Sequest, commercial proteomics search engines
Free layer
open-source